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| Chemical Name |
三烯生育酚γ-Tocotrienol
|
| CAS Number |
14101-61-2
|
| Qty 1 |
5mg
|
| Qty 2 |
25mg
|
| Synonym |
3,4-dihydro-2,7,8-trimethyl-2R-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol
|
| References |
| CAS Number |
14101-61-2 |
| Molecular Formula |
C28H42O2 |
| Formula Weight |
410.6 |
| Formulation |
A solution in ethanol |
| Purity |
>98% |
| λmax |
297 nm |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice in continental US; may vary elsewher |
| SMILES |
C/C(=C\CCC1(C)CCc2cc(O)c(C)c(C)c2O1)/CC/C=C(\C)/CCC=C(C)C |
Description
The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1 Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2 Spontaneously hypertensive rats fed a diet which includes γ-tocotrienol show significant reduction of systolic blood pressure and an increase of nitric oxide synthase activity in blood vessels.3 γ-Tocotrienol at 20 µM induces apoptosis of malignant sympathoadrenal (+SA) murine mammary epithelial cells.4
1 Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).
2 Osakada, F., Hashino, A., Kume, T., et al. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 904-915 (2004).
3 Shah, S., and Sylvester, P.W. Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells. Exp Biol Med 229 745-755 (2004).
4 Newaz, M.A., Yousefipour, Z., Nawal, N., et al. Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: Antioxidant protection by γ-tocotrienol. J Physiol Pharmacol 54(3) 319-327 (2003).
其它相关产品：
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α-Tocotrienol
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三烯生育酚γ-Tocotrienol
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δ-Tocotrienol
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