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三烯生育酚 α-Tocotrienol
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产品: 浏览次数:936三烯生育酚 α-Tocotrienol 
品牌: 进口
产品型号: 58864-81-6
产品规格: 10mg
最小起订量: 10 mg
供货总量:
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2022-12-26 10:54
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详细信息

Cat. Number
080197854552932
Chemical Name
三烯生育酚 α-Tocotrienol
CAS Number
58864-81-6
Qty 1
5mg
Qty 2
25mg
References
Formal Name 3,4-dihydro-2,5,7,8-tetramethyl-2R-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)]-2H-1-benzopyran-6-ol
CAS Number 58864-81-6
Molecular Formula C29H44O2
Formula Weight 424.7
Formulation A solution in ethanol
Purity >98%
λmax 289 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewher
SMILES C/C(=C\CCC1(C)CCc2c(O1)c(C)c(C)c(O)c2C)/CC/C=C(\C)/CCC=C(C)C
Size Global Purchasing
1 mg  
5 mg  
10 mg  
25 mg  

Description

The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1 Tocotrienols are found at high concentrations in palm oil and rice bran. Recent studies show tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2 Compared to other tocotrienols, α-tocotrienol exhibits the most potent neuroprotective actions in rat striatal neurons. At concentrations of 0.1-10 µM, α-tocotrienol significantly suppresses H2O2-induced cell death and provides protection against S-nitrocysteine-induced cell death and SIN-1 toxicity in a concentration dependent manner.2 HT4 cells, that are microinjected with 10−19 mol of α-tocotrienol into the cytosolic, are protected against glutamate-induced cell death by suppressing early activation of c-Src kinase and 12-lipoxygenase.3

1 Kamal-Eldin, A., and Appelqvist, L. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31 671-701 (1996).

2 Osakada, F., Hashino, A., Kume, T., et al. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 904-915 (2004).

3 Khanna, S., Roy, S., Slivka, S., et al. Neuroprotective properties of the natural vitamin E α-tocotrienol. Stroke 36 2258-2264 (2005).

其它相关产品:

α-Tocotrienol

三烯生育酚γ-Tocotrienol

δ-Tocotrienol


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