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| 产品： |
浏览次数：654YM201636 抑制剂 |
| 品牌： |
美国进口 |
| 产品型号： |
HY4802 |
| 产品规格： |
1mg.5mg |
| 最小起订量： |
1 mg |
| 供货总量： |
1000 mg |
| 发货期限： |
自买家付款之日起 3 天内发货 |
| 有效期至： |
长期有效 |
| 最后更新： |
2022-12-22 16:24 |
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Description
YM201636 is an inhibitor of PIKfyve, decreasing the synthesis of phosphatidylinositol 3,5-disphosphate. YM210636 decreases muscular contraction-stimulated glucose uptake in vitro and induces autophagy-dependent neuronal death in other cellular models. Additionally, YM210636 inhibits endomembrane transport and retroviral budding in vitro.
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| Specifications |
| Product ID |
HY4802 |
| Product Name |
YM201636 |
| Formula Wt. |
469.50 |
| Store Temp |
-20°C |
| References |
Liu Y, Lai YC, Hill EV, et al. Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle. Biochem J. 2013 Oct 15;455(2):195-206. PMID: 23905686.
Martin S, Harper CB, May LM, et al. Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death. PLoS One. 2013;8(3):e60152. PMID: 23544129.
Jefferies HB, Cooke FT, Jat P, et al. A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. EMBO Rep. 2008 Feb;9(2):164-70. PMID: 18188180. |
Shanghai HuicH Biotech Co.，Ltd.
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