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您当前的位置:首页 » 供应产品 » 美国原装进口γ-生育三烯酚 gamma-Tocotrienol
美国原装进口γ-生育三烯酚 gamma-Tocotrienol
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产品: 浏览次数:831美国原装进口γ-生育三烯酚 gamma-Tocotrienol 
品牌: 进口
产品型号: 14101-61-2
产品规格: 1mg,5mg,10mg
最小起订量: 1 mg
供货总量: 100 mg
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2024-07-03 09:43
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详细信息
 
Description
Tocotrienols contain an arene ring, a chromanol ring, and an isoprenoid tail; all tocotrienol compounds contain a methyl group on C8 of the arene ring. γ-Tocotrienol contains one additional methyl group on the arene ring, positioned ortho to C8. Tocotrienols are members of the vitamin E family, typically isolated from natural sources such as vegetable oils, nuts, and grains. Tocotrienols exhibit strong antioxidative, antiangiogenic, anticancer, and lipid-lowering qualities, although γ-Tocotrienol displays the strongest lipid-lowering activity of all of the tocotrienol compounds. Tocopherols, common substituents of over-the-counter vitamin E supplements, interfere with tocotrienol activity and show weaker antioxidative effects. Tocotrienols exhibit significant radical recycling abilities in cellular models of lipid peroxidation and oxidative damage and suppress HMG-CoA reductase activity. In vitro, these compounds induce apoptosis through inhibition of Id1, EGFR, and NF-κB, and also inhibit vessel formation and proliferation in aortic endothelial cells.
Specifications
Cas No. 14101-61-2
Product ID HT5610
Product Name gamma-Tocotrienol   美国原装进口γ-生育三烯酚  gamma-Tocotrienol
Synonym gamma-Tocotrienol, γ-Tocotrienol
Formula Wt. 410.63
Purity >98%
Store Temp -20°C
References Yap WN, Chang PN, Han HY, et al. Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways. Br J Cancer. 2008 Dec 2;99(11):1832-41. PMID: 19002171. 

Sen CK, Khanna S, Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 2006 Mar 27;78(18):2088-98. PMID: 16458936. 

Inokuchi H, Hirokane H, Tsuzuki T, et al. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317. 

Parker RA, Pearce BC, Clark RW, et al. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388. 

Serbinova E, Kagan V, Han D, et al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991;10(5):263-75. PMID: 1649783.
相关产品:三烯生育酚 delta-Tocotrienol



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