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Shanghai HuicH Biotech Co.，Ltd.
上海惠诚生物2010年至今专注于食品检测方面的标准品,优势品牌系列:
药物: TRC LGC USP LKT Focus
植提标准品: Extrasynthese PhytoLab Chromadex CaroteNature
糖类: Elicityl TDB Ludger Megazyme Glycarbo
脂类: Nu-Chek Larodan Avanti Matreya
其他: TCI ERM Wako Jackson Cayman laysan
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Description
SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7; this inhibition leads to inhibition of activin and TGF-β signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542 exhibits anti-angiogenic and anticancer activity. In vitro, SB-431542 inhibits proliferation and motility of gliomas cells. This compound also induces maturation of dendritic cells through its inhibition of TGF-β, increasing IL-12 production and increasing cytotoxic activity of immune cells in vitro.
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