上海惠诚生物科技有限公司

 

Description Moclobemide is a reversible inhibitor of MAO-A that exhibits antidepressant, anti-inflammatory, antinociceptive, and neuromodulatory activities. Moclobemide decreases immobility time in animals undergoing the forced swim test and suppresses LPS-induced increases in IL-1β and TNF-α expression in glial cells. Additionally, moclobemide increases latency time in animal models of thermal pain through an α2-adrenergic receptor-mediated pathway. Moclobemide also induces hippocampal neurogenesis, upregulating progenitor cell proliferation and expression of BDNF in vitro.

Specifications

Cas No. 71320-77-9 Product ID HM5610 Product Name 马氯贝胺分析标准品   Moclobemide   Formula Wt. 268.74 Store Temp Ambient References Bielecka AM, Paul-Samojedny M, Obuchowicz E. Moclobemide exerts anti-inflammatory effect in lipopolysaccharide-activated primary mixed glial cell culture. Naunyn Schmiedebergs Arch Pharmacol. 2010 Dec;382(5-6):409-17. PMID: 20811738.  Li YF, Zhang YZ, Liu YQ, et al. Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Acta Pharmacol Sin. 2004 Nov;25(11):1408-12. PMID: 15525460.  Schreiber S, Getslev V, Weizman A, et al. The antinociceptive effect of moclobemide in mice is mediated by noradrenergic pathways. Neurosci Lett. 1998 Sep 11;253(3):183-6. PMID: 9792241.  Ferigolo M, Barros HM, Marquardt AR, et al. Comparison of behavioral effects of moclobemide and deprenyl during forced swimming. Pharmacol Biochem Behav. 1998 Jun;60(2):431-7. PMID: 9632226.

 

Shanghai HuicH Biotech Co.，Ltd.
上海惠诚生物2010年至今专注于食品检测方面的标准品,优势品牌系列:
药物: TRC LGC USP LKT Focus
植提标准品: Extrasynthese PhytoLab Chromadex CaroteNature
糖类: Elicityl TDB Ludger Megazyme Glycarbo
脂类: Nu-Chek Larodan Avanti Matreya
其他: TCI ERM Wako Jackson Cayman laysan
手机微信：17715331663 QQ:2303607288