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| 产品： |
浏览次数：317桔皮素分析标准品 Tangeretin |
| 品牌： |
进口 |
| 产品型号： |
481-53-8 |
| 产品规格： |
5mg 10mg |
| 最小起订量： |
5 mg |
| 供货总量： |
100 mg |
| 发货期限： |
自买家付款之日起 3 天内发货 |
| 有效期至： |
长期有效 |
| 最后更新： |
2023-07-26 11:42 |
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Shanghai HuicH Biotech Co.，Ltd.
上海惠诚生物2010年至今专注于食品检测方面的标准品,优势品牌系列:
药物: TRC LGC USP LKT Focus
植提标准品: Extrasynthese PhytoLab Chromadex CaroteNature
糖类: Elicityl TDB Ludger Megazyme Glycarbo
脂类: Nu-Chek Larodan Avanti Matreya
其他: TCI ERM Wako Jackson Cayman laysan
手机微信：17715331663 QQ:2303607288
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Description
Tangeretin is a polymethoxy flavonoid isolated from citrus fruits. This compound exhibits a wide variety of health-related benefits, including anti-inflammatory, anti-allergy, anti-diabetic, and anticancer activities. In an in vivo model of skin-base allergic reaction, administration of tangeretin inhibits expression of IL-4 and TNF-alpha as well as inhibiting activation of NF-kB, AP-1, and p38. In both in vitro and in vivo models of diabetes mellitus, tangeretin increased AMP-K phosphorylation and glucose uptake and altered secretion of adipocytokines such as leptin, adiponectin, resistin, IL-6, and MCP-1. Additionally, this compound induced cell cycle arrest and inhibited proliferation of several cancer cell lines. Tangeretin also inhibits osteoclast formation, suggesting potential benefit as a treatment for bone diseases.
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| Specifications |
| Cas No. |
481-53-8 |
| Product ID |
HT0253 |
| Product Name |
桔皮素分析标准品 Tangeretin |
| Formula |
C20H20O7 |
| Formula Wt. |
372.37 |
| Purity |
≥98% |
| References |
Jang SE, Ryu KR, Park SH, et al. Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. Int Immunopharmacol. 2013 Aug 9;17(3):502-507. PMID: 23938254.
Tominari T, Hirata M, Matsumoto C, et al. Polymethoxy flavonoids, nobiletin and tangeretin, prevent lipopolysaccharide-induced inflammatory bone loss in an experimental model for periodontitis. J Pharmacol Sci. 2012;119(4):390-4. PMID: 22850615.
Kim MS, Hur HJ, Kwon DY, et al. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice. Mol Cell Endocrinol. 2012 Jul 6;358(1):127-34. PMID: 22476082.
Morley KL, Ferguson PJ, Koropatnick J. Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett. 2007 Jun 18;251(1):168-78. PMID: 17197076. |
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