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生化意义编辑
乙酰辅酶A是辅酶A的乙酰化形式,可以看作是活化了的乙酸。基团(CH3CO- =乙酰基)与辅酶A的半胱氨酸残基的SH-基团相连。这其实是高能键硫酯键。它是脂肪酸的beta-氧化及糖酵解后产生的丙酮酸氧化脱羧的产物。在许多代谢过程中起着关键的作用。
乙酰辅酶A是能源物质代谢的重要中间代谢产物,在体内能源物质代谢中是一个枢纽性的物质。糖、脂肪、蛋白质三大营养物质通过乙酰辅酶A汇聚成一条共同的代谢通路——三羧酸循环和氧化磷酸化,经过这条通路彻底氧化生成二氧化碳和水,释放能量用以ATP的合成。乙酰辅酶A是合成脂肪酸、酮体等能源物质的前体物质,也是合成及其衍生物等生理活性物质的前体物质。
Cat. Number |
103241001
|
Chemical Name |
乙酰辅酶A Acetyl-Coenzyme A
|
Mol. Formula |
C23H35N7O17P3SLi3
|
Mol. Weight |
acetyl-CoA: Mr = 809.6, acetyl-CoA-Li3: Mr = 827.4
|
Qty 1 |
50mg
|
Qty 2 |
200mg
|
Application Notes |
85% acetyl-CoA (enzymatic and absorbance), 2% Li
|
Solubility |
50 mg/ml in phosphate buffer, pH 7, is stable for 3 weeks at -15 to -25°C. Unfrozen solutions should be immediately used.
|
Storage condition |
stable at +2 to +8°C; no decomposition detectable within 6 m
|
References |
Used to assay CAT enzyme activity in cell extracts using radioisotopes. CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetylcoenzyme A to chloramphenicol. A number of assays have been developed to measure CAT activity in cell extracts |
Cat. Number |
10103241001
|
Chemical Name |
乙酰肉碱转移酶 Carnitine Acetyltransferase from pigeon breast muscle
|
Qty 1 |
5mg
|
References |
Product DescriptionAcetyl-CoA: carnitine O-acetyltransferase
EC 2.3.1.7 Specific activity:approx. 80 U/mg at 25°C with CoA and acetyl-D,L-carnitine as the substrates ContentsSuspension in 2.9 M ammonium sulfate solution, 50 mM K-phosphate, 1 mM EDTA, pH approximately 7.5
QualityContaminants:<0.01% acetyl-CoA-deacylase
|
Cat. Number |
L1754
|
Chemical Name |
脂肪酶 来源于皱褶假丝酵母Lipase from Candida rugosa
|
CAS Number |
9001-62-1
|
Application Notes |
Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.
|
Synonym |
三酰基甘油脂肪酶 三酰基甘油酰基水解酶
|
References |
One unit will hydrolyze 1.0microequivalent of fatty acid from a triglyceride in 1hr at pH7.2 at 37°C. (This is equivalent to approx. 10microliters of CO2in 30minutes.) |
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