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乙酰辅酶A是辅酶A的乙酰化形式，可以看作是活化了的乙酸。 基团 (CH3CO- = 乙酰基)与辅酶A的半胱氨酸残基的SH-基团相连。这其实是高能键硫酯键。它是脂肪酸的beta-氧化及糖酵解后产生的丙酮酸氧化脱羧的产物。在许多代谢过程中起着关键的作用。
乙酰辅酶A是人体内重要的化学物质。首先，丙酮酸氧化脱羧，脂酸的β-氧化的产物。同时，它是脂酸合成，合成和酮体生成的碳来源。三大营养物质的彻底氧化殊途同归，都会生成乙酰辅酶A以进入三羧酸循环。
乙酰辅酶A是能源物质代谢的重要中间代谢产物，在体内能源物质代谢中是一个枢纽性的物质。糖、脂肪、蛋白质三大营养物质通过乙酰辅酶A汇聚成一条共同的代谢通路——三羧酸循环和氧化磷酸化，经过这条通路彻底氧化生成二氧化碳和水，释放能量用以ATP的合成。乙酰辅酶A是合成脂肪酸、酮体等能源物质的前体物质，也是合成及其衍生物等生理活性物质的前体物质。
| Cat. Number |
10103241001
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| Chemical Name |
乙酰肉碱转移酶 Carnitine Acetyltransferase from pigeon breast muscle
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| Qty 1 |
5mg
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| References |
Product DescriptionAcetyl-CoA: carnitine O-acetyltransferase
EC 2.3.1.7 Specific activity: approx. 80 U/mg at 25°C with CoA and acetyl-D,L-carnitine as the substrates ContentsSuspension in 2.9 M ammonium sulfate solution, 50 mM K-phosphate, 1 mM EDTA, pH approximately 7.5
QualityContaminants:<0.01% acetyl-CoA-deacylase
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下一个：脂肪酶 来源于皱褶假丝酵母上一个：乙酰辅酶A,Acetyl-Coenzyme A
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| Cat. Number |
103241001
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| Chemical Name |
乙酰辅酶A Acetyl-Coenzyme A
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| Mol. Formula |
C23H35N7O17P3SLi3
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| Mol. Weight |
acetyl-CoA: Mr = 809.6, acetyl-CoA-Li3: Mr = 827.4
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| Qty 1 |
50mg
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| Qty 2 |
200mg
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| Application Notes |
85% acetyl-CoA （enzymatic and absorbance）, 2% Li
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| Solubility |
50 mg/ml in phosphate buffer, pH 7, is stable for 3 weeks at -15 to -25°C. Unfrozen solutions should be immediately used.
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| Storage condition |
stable at +2 to +8°C; no decomposition detectable within 6 m
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| References |
Used to assay CAT enzyme activity in cell extracts using radioisotopes. CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetylcoenzyme A to chloramphenicol. A number of assays have been developed to measure CAT activity in cell extracts |
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