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Cinacalcet364782-34-3惠诚生物供应
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产品: 浏览次数:56Cinacalcet364782-34-3惠诚生物供应 
品牌: 进口
产品型号: 364782-34-3 Cinacalcet Hydrochloride
产品规格: 5mg 25mg
最小起订量: 5 mg
供货总量: 100 mg
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2024-12-26 13:23
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详细信息
 上海惠诚生物为广大科研用户提供科学仪器,试剂耗材等专业科研产品服务。

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Description
Cinacalcet is an agonist at Ca2+-sensing receptors that is clinically used to treat secondary hyperparathyroidism with chronic kidney disease. Cinacalcet also displays anti-fibrotic activity. This compound decreases levels of parathyroid hormone (PTH), increases adiponectin secretion, and lowers oxidative stress. This compound increases sensitivity of Ca2+-sensing receptors to serum Ca2+ levels. In vivo, cinacalcet decreases renal epithelial-to-mesenchymal transition (EMT) and prevents the development of renal fibrosis.
Specifications
Cas No. 364782-34-3
Product ID C3352
Product Name Cinacalcet Hydrochloride
Formula C22H22F3N HCl
Formula Wt. 393.87
Store Temp Ambient
References Kuczera P, Adamczak M, Machnik G, et al. Treatment with Cinacalcet Increases Plasma Adiponectin Concentration in Hemodialysed Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism. Endocr Pract. 2015 Mar 18:1-22. [Epub ahead of print]. PMID: 25786554.

Wu M, Tang RN, Liu H, et al. Cinacalcet attenuates the renal endothelial-to-mesenchymal transition in rats with adenine-induced renal failure. Am J Physiol Renal Physiol. 2014 Jan 1;306(1):F138-46. PMID: 24154694.
 
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